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Boyoi's father, a Murle tribal chief and military commander within the Sudan People's Liberation Movement/Army (SPLM/A) was killed in 1989. After her father's death, she and her family spent a number of years in displaced camps in Sudan and refugee camps in Ethiopia to avoid conflicts of the war. She continued her higher education in Kenya and completed a series of diploma courses. In 2002, she began working for humanitarian relief agencies in various locations throughout South Sudan. In 2005 she founded ABONA International, a nonprofit organization aimed at supporting peace throughout South Sudan and providing assistance to girls and young women in violent and destructive situations. In 2007 she began work on her first music project, “Referendum” Boyoi is currently the executive director and founder of Voice of the Peace (VOP), a national NGO that provides psychosocial support and referral pathways for medical care to survivors of Gender-Based Violence (GBV). In January 2010, Boyoi was nominated by members of the Murle community to run for a parliamentary seat in the Southern Sudan Legislative Assembly in Juba. She campaigned for the elections that took place in April, 2010. Zooz, a song from Boyoi's yet to be released second album was featured on Sudan Votes Music Hopes in March 2010. Sudan Votes Music Hopes is a collaboration of artists from across Sudan that wrote election songs "to encourage the people of Sudan to make a mark on their future". The SVMH album was compiled by German singer songwriter Max Herre and is being distributed across Sudan on audio cassettes, radio and digitally via sudanvotes.com. The production was realized by Media in Cooperation and Transition (MICT) and was financed by the German Foreign Office. In August 2012, the Süd Electronic label released a vinyl with house remixes by Tama Sumo and Portable.